Details of Educational Qualification:

Work Experience:

Profile:  

Prof. Cinu Thomas A, completed B Pharm from Bangalore University, M. Pharm from Tamilnadu Dr MGR Medical University, Chennai and PhD in Pharmaceutical chemistry from Manipal University, Karnataka. She also bagged MBA in Pharma Management from ICFAI University Sikkim and Post Graduate Diploma in Patent Law from NALSAR University of Law, Hyderabad. She started her career as Vice principal in AM College of Pharmacy Karunagappally and Caritas college of Pharmacy, Kottayam. In 2004 she joined as a faculty member in Dept of Pharmaceutical Sciences, Mahatma Gandhi University later known as Centre for Professional and Advanced Studies- CPAS. From October 2020 onwards she is serving as Professor and Vice Principal of Caritas College of Pharmacy, Kottayam.

Dr Cinu is an excellent academician, researcher and expert in Molecular modeling using drug design software (Schrodeiger, Sybyl, V Life etc.), 3D QSAR techniques like Comfa, Comsia, Modern synthetic techniques, Spectral Analysis and Interpretation (Proton NMR, 13C NMR, GCMS, LCMS, FTIR, etc), Chromatographic techniques, Analytical method developments of drug molecules, Isolation and purification of molecules of natural origin, Biological Screening Techniques (Alamar blue assay, MTT assay, MGIT assay, anti- bacterial screening, anti -TB screening, cell culture etc), Biostatistics, and Patent drafting, 

She is having more than 20 peer reviewed national and international publication in her credit. Her current Scopus H index is 10

Publications: 

Jose, S.; Cinu, T.A.; Sebastian, Rosmy.; Shoja, M.H.; Aleykutty, N.A.; Durazzo, A.; Lucarini, M.; Santini, A.; Souto, E.B. Transferrin-Conjugated Docetaxel–PLGA Nanoparticles for Tumor Targeting: Influence on MCF-7 Cell Cycle. Polymers 2019, 11, 1905. Impact Facor-3.614

Amol B. Khade, Sidhartha S. Kar, A Cinu Thomas , Ashutosh Tiwari, Mradul Tiwari, K. E. Vandana , Pritesh Bhat, G. Varadaraj Bhat , G. Gautham Shenoy. (2020). Synthesis, Biological Evaluation and Molecular Dynamics Simulation Studies of Novel Diphenyl Ethers. Medicinal Chemistry. 16(2) 256-270(15) Impact Factor 2.53

Sidhartha S. Kar, Cinu Thomas A. (2019). Strategically placed trifluoromethyl substituent in the realm of antitubercular drug design. Current Drug Therapy. 14(2)114-123(10) Impact factor 2.078

Nila MV, V Senthil, S Jose, Cinu Thomas A, Jyoti H. (2020). Development and validation of a specific RP-HPLC method for simultaneous estimation of antiretroviral drugs: Application to nanoparticulate formulation system. Current Pharmaceutical Analysis. 16 (1)12-23(12). Impact factor-0.859

Jose. S,Rosmy, S., Cinu, T.A., Jyoti, H., Aleykutty, N.A, (2016).Ligand conjugated tumor-targeted nanoparticle drug delivery system of vincristine: 32 full factorial design and in vitro evaluation. Der Pharmacia Lettre. 8 (3):197-203. Impact factor-1.96

Jose, S, Juna BC, Cinu TA, Jyoti H, Aleykutty NA. 2016. Carboplatin Loaded Surface Modified PLGA Nanoparticles: Optimization, Characterization, and in Vivo Brain Targeting Studies. Colloids and surfaces. B, Biointerfaces 142: 307–14. Impact Factor-4.15.

Cinu Thomas A, S. Kar Sidhartha, Bairy Indira, Bhat G. Varadaraj, P. Shenoy Vishnu, G. Gautham Shenoy.(2015). Design, synthesis and evaluation of antitubercularactivity of Triclosan analogues. Arabian Journal of Chemistry. (in press) https://doi.org/10.1016/j.arabjc.2015.09.003 Impact factor-2.969

Cinu Thomas A., Siddhartha S. Kar, Indira Bairy, Varadaraj Bhat G, Vishnu P. Shenoy, G. Gautham Shenoy. (2015). Synthesis and Evaluation of Antitubercular Activity of Novel Diphenyl Ether Derivatives. Indo Global Journal of Pharmaceutical Sciences, 5(1): 19-25.

Jose, S., Sowmya, S., Cinu, T. A., Aleykutty, N. A., Thomas, S. &Souto, E. B. (2014). Surface modified PLGA nanoparticles for brain targeting of Bacoside-A. European Journal of Pharmaceutical Sciences, 63, 29-35.Impact factor-3.35

Jose, S., Anju, S. S., Cinu, T. A., Aleykutty, N. A., Thomas, S. &Souto, E. B. (2014). In vivo pharmacokinetics and biodistribution of resveratrol-loaded solid lipid nanoparticles for brain delivery. International Journal of Pharmaceutics, 474, 6-13.Impact factor-3.65

117. V. Nila, M. R. Sudhir, T. A. Cinu, N. A. Aleykutty, and S. Jose., (2014). Floating microspheres of carvedilol as gastro retentive drug delivery system: 32 full factorial design and in vitro evaluation. Drug Delivery. 21:2, 110-117. DOI. 10.3109/10717544.2013.834414Impact factor-2.56

Jose, S., Fangueiro, J.F., Smitha, J., Cinu, T.A., Chacko, A.J., Premaletha, K., Souto, E.B.,2012. Predictive modelling of insulin release profile from cross-linked chitosan microspheres. European Journal of Medicinal Chemistry. 92, 175-179, DOI: 10.1016/j.ejmech.2012.12.011Impact Factor-3.45

Jose, S., Ansa, C.R., Cinu, T.A., Chacko, A.J., Aleykutty, N.A., Ferreira, S.V., Souto, E.B. 2013. Thermo-sensitive gels containing lorazepam microspheres for intranasal brain targeting. International Journal of Pharmaceutics, 441(1), 516-526. DOI: 10.1016/j.ijpharm.2012.10.049Impact Factor-3.65

179. Jose, J.F. Fangueiro, J. Smitha, T.A. Cinu, A.J. Chacko, K. Premaletha, E.B. Souto.(2012) Cross-linked chitosan microspheres for oral delivery of insulin: Taguchi design and in vivo testing. Colloids and Surfaces B: Biointerface. 92;175-179.Impact factor-4.15

Kunjachan, S., Jose, S.,Thomas, C. A., Joseph, E., Kiessling, F. and Lammers, T. (2012), Physicochemical and biological aspects of macrophage-mediated drug targeting in antimicrobial therapy. Fundamental & Clinical Pharmacology, 26: 63–71. doi: 10.1111/j.1472-8206.2011.00955.xImpact factor-2.12

4. Jose, M.T. Prema, A.J. Chacko, A. Cinu Thomas, E.B. Souto. (2011) Colon-specific chitosan microspheres for chronotherapy of chronic stable angina. Colloids and Surfaces B: Biointerfaces. 83; 277–283Impact factor-4.15

Jose S., K. Dhanya, T.A. Cinu and N. A. Aleykutty.(2010). Multiparticulate System for Colon Targeted Delivery of Ondansetron. Indian Journal of Pharmaceutical Sciences.72:58-64Impact factor-0.45

Jose Sajan, Dhanya K, Cinu TA, Litty Joseph Chacko AJ. (2009) Colon targeted drug delivery: Different Approaches.  Journal of Young Pharmacist 1(1):13-19.

Jose Sajan, Dhanya K, Cinu TA,Litty Joseph Chacko AJ. (2009) Colon targeted drug delivery: Different Approaches.Journal of Young Pharmacist 1(1):13-19.Impact Factor-0.45

Chacko AJ, Jose Sajan, Litty Joseph,Cinu TA, NA Aleykutty. (2009) Formulation and evaluation of Mesalamine matrix tablets using natural polymers for colonic controlled delivery. International Journal of Pharma Research 1:29-34.

J Sajan, TA Cinu, AJ Chacko, J Litty, T Jaseeda. (2009). Chronotherapeutics and chronotherapeutic drug delivery systems. Tropical Journal of Pharmaceutical Research. 8(5):467-475.

A Cinu Thomas, GVS Rama Sarma (1999) Analgesic and anti-inflammatory activity of Melia dubia bark. Indian Drugs 36(3)203-205.

Thomas A Cinu, GVS Rama Sarma (1999) Preliminary phytochemical and antimicrobial investigations on Melia dubia bark. Ancient Science of Life 19 (1&)1-5.